Y. Fujii, Y. Ochi, M. Tuchiya, M. Kajita, Y. Fujita, Y. Ishimoto, T. Okajima*, Spontaneous spatial correlation of elastic modulus in jammed epithelial monolayers observed by AFM, Biophysical Journal (2019).[paper]
H. Nishino*, M. Domae, T. Takanashi, T. Okajima, Cricket tympanal organ revisited: morphology, development, and possible functions of the adult-specific chitin core beneath the anterior tympanal membrane, Cell and Tissue Research (2019).
Y. Fujii, T. Okajima* , Calibrating the Young’s modulus of soft materials with surface tilt angle measured by atomic force microscopy, AIP Advances 9, 015028 (2019).[paper]
M. Tanaka#, Y. Fujii#, K. Hirano, T. Higaki, A. Nagasaki, R. Ishikawa, T. Okajima, K. Katoh* (# equal contribution), Fascin in lamellipodia contributes to cell elasticity by controlling the orientation of filamentous actin, Genes to Cells (2019). [paper]
Y. Miyatake*, K. Kuribayashi-Shigetomi*, Y. Ohta, S. Ikeshita, A. Subagyo, K. Sueoka, A. Kakugo, M. Amano, T. Takahashi, T. Okajima, M. Kasahara, Visualising the dynamics of live pancreatic microtumours self-organised through cell-in-cell invasion, Scientific Reports 8, 14054 (2018). [paper]
A. Tanaka*, Y. Fujii, N. Kasai, T. Okajima, H. Nakashima, Regulation of Neuritogenesis in Hippocampal Neurons using Stiffness of Extracellular Microenvironment. PLOS ONE 13, e0191928(2018) [paper]
Q. He, T. Okajima, H. Onoe, A. Subagyo, K. Sueoka, K. Kuribayashi-Shigetomi*, Origami-based self-folding of co-cultured NIH/3T3 and HepG2 cells into 3D microstructures, Scientific Reports 8, 4556 (2018) [paper]
P.G. Cai, R. Takahashi, K. Kuribayashi-Shigetomi, A. Subagyo, K. Sueoka, J. M. Maloney, K. J. Van Vliet, T. Okajima*, Temporal Variation in Single-Cell Power-Law Rheology Spans the Ensemble Variation of Cell Population, Biophysical Journal 113, 671-678 (2017) . [paper] (This paper was highlighted in BJ.)
S.‑O. Kim, J. Kim, T. Okajima and N.‑J. Cho*, Mechanical properties of paraformaldehyde‑treated individual cells investigated by atomic force microscopy and scanning ion conductance microscopy. Nano Convergence 4, 5 (2017).[paper]
R. Takahashi, T. Okajima*, Comparison between power-law rheological parameters of living cells in frequency and time domains measured by atomic force microscopy. Japanese Journal of Applied Physics 55, 08NB22 (2016).[paper]]
T. Okajima，Nanorheology of Living Cells (Chapter 13, The World of Nano-Biomechanics, A. Ikai, Elsevier） (2016)
R. Takahashi, T. Okajima*, Mapping power-law rheology of living cells using multi-frequency force modulation atomic force microscopy, Applied Physics Letters 107, 173702 (2015).[paper]
A. Tanaka*, R. Tanaka, N. Kasai, S. Tsukada, T. Okajima, K. Sumitomo, Time-lapse imaging of morphological changes in a single neuron during the early stages of apoptosis using scanning ion conductance microscopy, Journal of Structural Biology 191, 32–38 (2015). [paper]
P.G. Cai, T. Okajima*, Precision of cell-to-cell variation in power-law rheology characterized by atomic force microscopy, Japanese Journal of Applied Physics 54, 037001(2015)[paper]
T. Okajima, Atomic Force Microscopy: Imaging and Rheology of Living Cells (Nano/Micro Science and Technology in Biorheology: Principles, Methods, and Applications Chapter 15 (387-414), Springer, 2015)[book]
K. Kuribayashi-Shigetomi, R. Takahashi, A. Subagyo, K. Sueoka, T. Okajima, High-throughput measurements of single cell rheology by atomic force microscopy (Hyper Bio Assembler for 3D Cellular Systems, Chapter 4 (57-67), Springer, 2015)[book]
M. Kajita, K. Sugimura, A. Ohoka, J. Burden, H. Suganuma, M. Ikegawa, T. Shimada, T. Kitamura, M. Shindoh, S. Ishikawa, S. Yamamoto, S. Saitoh, Y. Yako, R. Takahashi, T. Okajima, J. Kikuta, Y. Maijima, M. Ishii, M. Tada, and Y. Fujita*, Filamin acts as a key regulator in epithelial defence against transformed cells, Nature Communications 5, 4428(2014)[paper]
R.Takahashi, S. Ichikawa, A. Subagyo, K. Sueoka, and T. Okajima*, Atomic force microscopy measurements of mechanical properties of single cells patterned by microcontact printing, Advanced Robotics 28, 449-455(2014) [paper]
P.G. Cai, Y. Mizutani, M. Tsuchiya, J. M. Maloney, B. Fabry, K. J. Van Vliet, T. Okajima*, Quantifying Cell-to-Cell Variation in Power-Law Rheology, Biophysical Journal 105 (2013) 1093-1102. [paper]
Y. Mizutani, M.-H. Choi, S.-J. Cho, T. Okajima*, Nanoscale fluctuations on epithelial cell surfaces investigated by scanning ion conductance microscopy, Applied Physics Letters 102 (2013) 173703 (4pages).[paper]
T. Okajima*, Atomic Force Microscopy for the Examination of Single Cell Rheology (Review), Current Pharmaceutical Biotechnology, 13(2012)2623-2631.
Y. Mizutani, K. Kawahara, T. Okajima*, Effect of Isoproterenol on Local Contractile Behaviors of Rat Cardiomyocytes Measured by Atomic Force Microscopy Current Pharmaceutical Biotechnology 13(2012)2599-2603.
A. Okada, Y. Mizutani, A. Subagyo, H. Hosoi, M. Nakamura, K. Sueoka, K. Kawahara, T. Okajima*,Direct observation of dynamic force propagation between focal adhesions of cells on microposts by atomic force microscopy. Appl. Phys. Lett. 99 (2011) 263703. [selected for the January 1, 2012 issue of Virtual Journal of Biological Physics Research]
Kunugi, S., Iwabuchi, S., Matsuyama, D., Okajima, T. and Kawahara*, K.Negative-feedback regulation of ATP release: ATP release from cardiomyocytes is strictly regulated during ischemia. Biochemical and Biophysical Research Communications, 416:409-415, 2011.
Niikura K*, Nambara K, Okajima T, Kamitani R, Aoki S, Matsuo Y, Ijiro K.
Artificial polymeric receptors on the cell surface promote the efficient cellular uptake of quantum dots, Org Biomol Chem. 9(2011)5787-92.
A. Miyaoka, Y. Mizutani, M. Tsuchiya, K. Kawahara, T. Okajima* Rheological Properties of Growth-Arrested Fibroblast Cells under Serum Starvation Measured by Atomic Force Microscopy. Jpn. J. Appl. Phys. 50 (2011)08LB16(4pages).
K. Niikura*, K. Nambara, T. Okajima, Y. Matsuo and K. Ijiro, Influence of Hydrophobic Structures on the Plasma Membrane Permeability of Lipidlike Molecules Langmuir 26 (2010) 9170
S. Hiratsuka, Y. Mizutani, P.G. Cai, M. Tsuchiya, H. Tokumoto, K. Kawahara, T. Okajima*, Statistics of Single Cell Mechanics Investigated by Atomic Force Microscopy The 2010 MRS Spring Meeting Symposium U proceedings in press.
S. Hiratsuka, Y. Mizutani, M. Tsuchiya, K. Kawahara, H. Tokumoto and T. Okajima*,The number distribution of complex shear modulus of single cells measured by atomic force microscopy,Ultramicroscopy Volume 109, Issue 8, July 2009, Pages 937-941.
R. Kamitani, K. Niikura*, T. Okajima, Y. Matsuo, K. Ijiro*, Design of cell-surface-retained polymers for artificial ligand display, Chembiochem 10(2009)230-233.
S. Hiratsuka, Y. Mizutani, A. Toda, N. Fukushima, K. Kawahara, H. Tokumoto and T. Okajima*, Power-Law Stress and Creep Relaxations of Single Cells Measured by Colloidal ProbeAtomic Force Microscopy Jpn. J. Appl. Phys. 48 (2009)08JB14-1-4
K. Shikinaka, H. Kwon, A. Kakugo, H. Furukawa, Y. Osada, J.P. Gong*, Y. Aoyama, H. Nishioka, H. Jinnai, T. Okajimaa, “Observation of the Three-Dimensional Structure of Actin Bundles formed with Polycations”, Biomacromolecules, 9, 537-542 (2008).
Y. Tanaka*, Y. Kawauchi, T. Kurokawa, H. Furukawa, T. Okajima, and J. P. Gong, “Localized Yielding around Crack Tips of Double-network Gels”, Macromol. Rapid Commun., 29, 1514-1520 (2008).
H. Yamamura, K. Kimura, T. Okajima, H. Tokumoto, Y. Watamabe*, “Affinity of Functional Groups for Membrane Surfaces: Implications for Physically Irreversible Fouling”, Environ. Sci. Technol. 42(2008) 5310-5315.
Y. Mizutani, M. Tsuchiya, S. Hiratsuka, K. Kawahara, H. Tokumoto and T. Okajima*, “Elasticity of Living Cells on a Microarray during the Early Stages of Adhesion Measured by Atomic Force Microscopy”, Jpn. J. Appl. Phys. 47(2008)6177-6180.
T. Okajima*, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura and H. Tokumoto, ” Stress Relaxation Measurement of Fibroblast Cells with Atomic Force Microscope “, Jpn. J. Appl. Phys. (2007) 5552-5555
T. Okajima*, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura and H. Tokumoto, “Stress relaxation of HepG2 cells measured by atomic force microscopy”, Nanotechnology 18 (2007) 084010
T. Okajima*, X.M. Tao, H. Azehara, H. Tokumoto, “Force Spectroscopy on Single Polymer Incorporated into Polymer Gels”, J. Nanosci. Nanotech. 7, 790?795 (2007).
H.-J. Kwon, A. Kakugo, T. Ura, T. Okajima, Y. Tanaka, H. Furukawa, Y. Osada and J.-P. Gong*, “Actin network formation by uni-directional polycation diffusion”, Langmuir 23(2007)6257-6262
K. Hiroaki, T. Takagi, T. Okajima, M. Kinjo*, “DNA microstructure based on self-assembly of 4-Sticky-End Holiday Junctions in Aqueous Solution “, J. Nanosci. Nanotech. 7(2007)726-729.