{"id":107,"date":"2014-03-20T16:37:44","date_gmt":"2014-03-20T07:37:44","guid":{"rendered":"http:\/\/hokudai-cell.cis-trans.com\/?page_id=107"},"modified":"2024-12-03T13:22:32","modified_gmt":"2024-12-03T04:22:32","slug":"publication-html","status":"publish","type":"page","link":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/publication-html\/","title":{"rendered":"Publication"},"content":{"rendered":"<ul>\n<li><strong>Takahiro Kotani, Tomohiro Matsuo, Megumi Yokobori, Yosuke Tsuboyama, Yuki Miyata, Yuki Fujii, Kaori Kuribayashi-Shigetomi, Takaharu Okajima*<\/strong>, Mapping single-cell rheology of ascidian embryos in the cleavage stages using AFM, bioRxiv (2024). <a class=\"blank\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.12.01.625795v1\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Toki Kaneshima, Masaki Ogawa, Takayoshi Yamamoto, Yosuke Tsuboyama, Yuki Miyata, Takahiro Kotani, Takaharu Okajima, Tatsuo Michiue*<\/strong>, Enhancement of neural crest formation by mechanical force in Xenopus development, International Journal of Developmental Biology 68, 25-37 (2024). <a class=\"blank\" href=\"https:\/\/ijdb.ehu.eus\/article\/230273tm\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Takahiro Kotani, Yuki Miyata, Yosuke Tsuboyama, Yuki Fujii, Takaharu Okajima*<\/strong>, Local Intracellular stiffening of ascidian embryo in cleavage developmental stage observed by atomic force microscopy, Japanese Journal of Applied Physics 63, 04SP64 (2024).<a class=\"blank\" href=\"https:\/\/iopscience.iop.org\/article\/10.35848\/1347-4065\/ad3760\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Yuki Miyata, Feng-Yueh Chan, Takayuki Uchihashi, Takaharu Okajima*<\/strong>, Compressed sensing reconstruction of cell mechanical images obtained from atomic force microscopy, Japanese Journal of Applied Physics, 63, 04SP46 (2024).<a class=\"blank\" href=\"https:\/\/iopscience.iop.org\/article\/10.35848\/1347-4065\/ad34de\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>K. Shigemura, K. Kuribayashi-Shigetomi, R. Tanaka, H. Yamasaki, and T. Okajima*<\/strong>, Mechanical properties of epithelial cells in domes investigated using atomic force microscopy, Frontiers in Cell and Developmental Biology 11, 1245296 (2023). <a class=\"blank\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2023.1245296\/full\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>T. Okajima*, K. Kuribayashi-Shigetomi, <\/strong> ,Atomic force microscopy for investigating cell and tissue mechanics as heterogeneous and hierarchical materials, Journal of Biomechanical Science and Engineering 18, 23-00339 (2023). <a class=\"blank\" href=\"https:\/\/www.jstage.jst.go.jp\/article\/jbse\/advpub\/0\/advpub_23-00339\/_article\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>H. Tsuru, C. Yoshihara, H. Suginobe, M. Matsumoto, Y. Ishii, J. Narita , R. Ishii, R. Wang, A. Ueyama, K. Ueda, M. Hirose, K. Hashimoto, H. Nagano, R. Tanaka, T. Okajima, K. Ozono, H. Ishida*<\/strong> ,Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy, Journal of the American Heart Association 12,e029676 (2023). <a class=\"blank\" href=\"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.123.029676?rfr_dat=cr_pub++0pubmed&amp;url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>M. Matsumoto#, H. Tsuru#, H. Suginobe#, J. Narita, R. Ishii, M. Hirose, K. Hashimoto, R. Wang, C. Yoshihara, A. Ueyama, R. Tanaka, K. Ozono, T. Okajima*, H. Ishida*<\/strong> (# equal contribution), Atomic force microscopy identifies the alteration of rheological properties of the cardiac fibroblasts in idiopathic restrictive cardiomyopathy,PLoS ONE 17, e0275296 (2022). <a class=\"blank\" href=\"https:\/\/journals.plos.org\/plosone\/article\/authors?id=10.1371\/journal.pone.0275296\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Y. Fujii, W.C. Koizumi, T. Imai, M. Yokobori, T. Matsuo, K. Oka, K. Hotta*, T. Okajima*<\/strong>, Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo, Communications Biology 4, 341 (2021). <a class=\"blank\" href=\"https:\/\/www.nature.com\/articles\/s42003-021-01869-w\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Y. M. Efremov*, T. Okajima, A. Raman<\/strong>, Measuring viscoelasticity of soft biological samples using atomic force microscopy, Soft Matter 16, 64-81(2020).<a class=\"blank\" href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2019\/sm\/c9sm01020c#!divAbstract\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong> R. Tanaka, M. Sawano, Y. Fujii, K. Kuribayashi-Shigetomi, A. Subagyo, K. Sueoka, T. Okajima*<\/strong>, Relationship between rheological properties and actin filaments of single cells investigated by atomic force microscopy, Japanese Journal of Applied Physics (2020).<a class=\"blank\" href=\"https:\/\/iopscience.iop.org\/article\/10.35848\/1347-4065\/ab8e23\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong> K. Toyota#, R. Tanaka#, T. Okajima* <\/strong>(# equal contribution), Stiffness of brewers&#8217; yeast under ethanol stress investigated by atomic force microscopy, Japanese Journal of Applied Physics 59, SN1005(2020).<a class=\"blank\" href=\"https:\/\/iopscience.iop.org\/article\/10.35848\/1347-4065\/ab87f3\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Y. Fujii, Y. Ochi, M. Tuchiya, M. Kajita, Y. Fujita, Y. Ishimoto, T. Okajima*<\/strong>, Spontaneous spatial correlation of elastic modulus in jammed epithelial monolayers observed by AFM, Biophysical Journal (2019).<a class=\"blank\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006349519301079\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>H. Nishino*, M. Domae, T. Takanashi, T. Okajima<\/strong>, Cricket tympanal organ revisited: morphology, development, and possible functions of the adult-specific chitin core beneath the anterior tympanal membrane, Cell and Tissue Research (2019).<\/li>\n<li><strong>Y. Fujii, T. Okajima* <\/strong>, Calibrating the Young\u2019s modulus of soft materials with surface tilt angle measured by atomic force microscopy, AIP Advances 9, 015028 (2019).<a class=\"blank\" href=\"https:\/\/aip.scitation.org\/doi\/10.1063\/1.5046372\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>M. Tanaka#, Y. Fujii#, K. Hirano, T. Higaki, A. Nagasaki, R. Ishikawa, T. Okajima, K. Katoh*<\/strong> (# equal contribution), Fascin in lamellipodia contributes to cell elasticity by controlling the orientation of filamentous actin, Genes to Cells (2019).&nbsp;<a class=\"blank\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/gtc.12671\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>A. Tanaka*, Y. Fujii, N. Kasai, T. Okajima, H. Nakashima<\/strong>, Regulation of Neuritogenesis in Hippocampal Neurons using Stiffness of Extracellular Microenvironment. PLOS ONE 13, e0191928(2018)&nbsp;<a class=\"blank\" href=\"http:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0191928\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Q. He, T. Okajima, H. Onoe, A. Subagyo, K. Sueoka, K. Kuribayashi-Shigetomi*<\/strong>, Origami-based self-folding of co-cultured NIH\/3T3 and HepG2 cells into 3D microstructures, Scientific Reports 8, 4556 (2018) <a class=\"blank\" href=\"https:\/\/www.nature.com\/articles\/s41598-018-22598-x\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>P.G. Cai, R. Takahashi, K. Kuribayashi-Shigetomi, A. Subagyo, K. Sueoka, J. M. Maloney, K. J. Van Vliet, T. Okajima*<\/strong>, Temporal Variation in Single-Cell Power-Law Rheology Spans the Ensemble Variation of Cell Population, Biophysical Journal 113, 671-678 (2017) . <a class=\"blank\" href=\"http:\/\/www.cell.com\/biophysj\/abstract\/S0006-3495(17)30675-6\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a> (This paper was highlighted in BJ.)<\/li>\n<li><strong>S.\u2011O. Kim, J. Kim, T. Okajima and N.\u2011J. Cho*<\/strong>, Mechanical properties of paraformaldehyde\u2011treated individual cells investigated by atomic force microscopy and scanning ion conductance microscopy. Nano Convergence 4, 5 (2017).<a href=\"https:\/\/nanoconvergencejournal.springeropen.com\/articles\/10.1186\/s40580-017-0099-9\">[paper]<\/a><\/li>\n<li><strong>R. Takahashi, T. Okajima*<\/strong>, Comparison between power-law rheological parameters of living cells in frequency and time domains measured by atomic force microscopy. Japanese Journal of Applied Physics 55, 08NB22 (2016).<a href=\"http:\/\/iopscience.iop.org\/article\/10.7567\/JJAP.55.08NB22\">[paper]<\/a><a class=\"blank\" href=\"http:\/\/iopscience.iop.org\/article\/10.7567\/JJAP.55.08NB22\" target=\"_blank\" rel=\"noopener noreferrer\">]<\/a><\/li>\n<li><strong>T. Okajima<\/strong>\uff0cNanorheology of Living Cells (Chapter 13, The World of Nano-Biomechanics, A. Ikai, Elsevier\uff09 (2016)<\/li>\n<li><strong>R. Takahashi, T. Okajima*<\/strong>, Mapping power-law rheology of living cells using multi-frequency force modulation atomic force microscopy, Applied Physics Letters 107, 173702 (2015).<a class=\"blank\" href=\"http:\/\/scitation.aip.org\/content\/aip\/journal\/apl\/107\/17\/10.1063\/1.4934874\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>A. Tanaka*, R. Tanaka, N. Kasai, S. Tsukada, T. Okajima, K. Sumitomo<\/strong>, Time-lapse imaging of morphological changes in a single neuron during the early stages of apoptosis using scanning ion conductance microscopy, Journal of Structural Biology 191, 32\u201338 (2015). <a class=\"blank\" href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S104784771530006X\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>P.G. Cai, T. Okajima*<\/strong>, Precision of cell-to-cell variation in power-law rheology characterized by atomic force microscopy, Japanese Journal of Applied Physics 54, 037001(2015)<a class=\"blank\" href=\"http:\/\/iopscience.iop.org\/1347-4065\/54\/3\/037001\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>T. Okajima<\/strong>, Atomic Force Microscopy: Imaging and Rheology of Living Cells (Nano\/Micro Science and Technology in Biorheology: Principles, Methods, and Applications Chapter 15 (387-414), Springer, 2015)<a class=\"blank\" href=\"http:\/\/link.springer.com\/chapter\/10.1007%2F978-4-431-54886-7_15\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>K. Kuribayashi-Shigetomi, R. Takahashi, A. Subagyo, K. Sueoka, T. Okajima<\/strong>, High-throughput measurements of single cell rheology by atomic force microscopy (Hyper Bio Assembler for 3D Cellular Systems, Chapter 4 (57-67), Springer, 2015)<a class=\"blank\" href=\"http:\/\/link.springer.com\/chapter\/10.1007%2F978-4-431-55297-0_4\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>M. Kajita, K. Sugimura, A. Ohoka, J. Burden, H. Suganuma, M. Ikegawa, T. Shimada, T. Kitamura, M. Shindoh, S. Ishikawa, S. Yamamoto, S. Saitoh, Y. Yako, R. Takahashi, T. Okajima, J. Kikuta, Y. Maijima, M. Ishii, M. Tada, and Y. Fujita*<\/strong>, Filamin acts as a key regulator in epithelial defence against transformed cells, Nature Communications 5, 4428(2014)<a class=\"blank\" href=\"http:\/\/www.nature.com\/ncomms\/2014\/140731\/ncomms5428\/full\/ncomms5428.html\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>R.Takahashi, S. Ichikawa, A. Subagyo, K. Sueoka, and T. Okajima*<\/strong>, Atomic force microscopy measurements of mechanical properties of single cells patterned by microcontact printing, Advanced Robotics 28, 449-455(2014)&nbsp;<a class=\"blank\" href=\"http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/01691864.2013.876933#.UxG77_R_vFg\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>P.G. Cai, Y. Mizutani, M. Tsuchiya, J. M. Maloney, B. Fabry, K. J. Van Vliet, T. Okajima*<\/strong>, Quantifying Cell-to-Cell Variation in Power-Law Rheology, Biophysical Journal 105 (2013) 1093-1102.&nbsp;<a class=\"blank\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006349513008576?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>Y. Mizutani, M.-H. Choi, S.-J. Cho, T. Okajima*<\/strong>, Nanoscale fluctuations on epithelial cell surfaces investigated by scanning ion conductance microscopy, Applied Physics Letters 102 (2013) 173703 (4pages).<a class=\"blank\" href=\"http:\/\/scitation.aip.org\/content\/aip\/journal\/apl\/102\/17\/10.1063\/1.4803469\" target=\"_blank\" rel=\"noopener noreferrer\">[paper]<\/a><\/li>\n<li><strong>T. Okajima*<\/strong>, Atomic Force Microscopy for the Examination of Single Cell Rheology (Review), Current Pharmaceutical Biotechnology, 13(2012)2623-2631.<\/li>\n<li><strong>Y. Mizutani, K. Kawahara, T. Okajima*<\/strong>, Effect of Isoproterenol on Local Contractile Behaviors of Rat Cardiomyocytes Measured by Atomic Force Microscopy Current Pharmaceutical Biotechnology 13(2012)2599-2603.<\/li>\n<li><strong>A. Okada, Y. Mizutani, A. Subagyo, H. Hosoi, M. Nakamura, K. Sueoka, K. Kawahara, T. Okajima*,<\/strong>Direct observation of dynamic force propagation between focal adhesions of cells on microposts by atomic force microscopy. Appl. Phys. Lett. 99 (2011) 263703. [selected for the January 1, 2012 issue of Virtual Journal of Biological Physics Research]<\/li>\n<li><strong>Kunugi, S., Iwabuchi, S., Matsuyama, D., Okajima, T. and Kawahara*, K.<\/strong>Negative-feedback regulation of ATP release: ATP release from cardiomyocytes is strictly regulated during ischemia. Biochemical and Biophysical Research Communications,&nbsp;416:409-415, 2011.<\/li>\n<li><strong>Niikura K*, Nambara K, Okajima T, Kamitani R, Aoki S, Matsuo Y, Ijiro K.<\/strong><br \/>\nArtificial polymeric receptors on the cell surface promote the efficient cellular uptake of quantum dots, Org Biomol Chem. 9(2011)5787-92.<\/li>\n<li><strong>A. Miyaoka, Y. Mizutani, M. Tsuchiya, K. Kawahara, T. Okajima*<\/strong>&nbsp;Rheological Properties of Growth-Arrested Fibroblast Cells under Serum Starvation Measured by Atomic Force Microscopy. Jpn. J. Appl. Phys. 50 (2011)08LB16(4pages).<\/li>\n<li><strong>K. Niikura*, K. Nambara, T. Okajima, Y. Matsuo and K. Ijiro<\/strong>, Influence of Hydrophobic Structures on the Plasma Membrane Permeability of Lipidlike Molecules Langmuir 26 (2010) 9170<\/li>\n<li><strong>S. Hiratsuka, Y. Mizutani, P.G. Cai, M. Tsuchiya, H. Tokumoto, K. Kawahara, T. Okajima*,<\/strong>&nbsp;Statistics of Single Cell Mechanics Investigated by Atomic Force Microscopy The 2010 MRS Spring Meeting Symposium U proceedings in press.<\/li>\n<li><strong>S. Hiratsuka, Y. Mizutani, M. Tsuchiya, K. Kawahara, H. Tokumoto and T. Okajima*<\/strong>,The number distribution of complex shear modulus of single cells measured by atomic force microscopy,Ultramicroscopy Volume 109, Issue 8, July 2009, Pages 937-941.<\/li>\n<li><strong>R. Kamitani, K. Niikura*, T. Okajima, Y. Matsuo, K. Ijiro*<\/strong>, Design of cell-surface-retained polymers for artificial ligand display, Chembiochem 10(2009)230-233.<\/li>\n<li><strong>S. Hiratsuka, Y. Mizutani, A. Toda, N. Fukushima, K. Kawahara, H. Tokumoto and T. Okajima*<\/strong>, Power-Law Stress and Creep Relaxations of Single Cells Measured by Colloidal ProbeAtomic Force Microscopy Jpn. J. Appl. Phys. 48 (2009)08JB14-1-4<\/li>\n<li><strong>K. Shikinaka, H. Kwon, A. Kakugo, H. Furukawa, Y. Osada, J.P. Gong*, Y. Aoyama, H. Nishioka, H. Jinnai, T. Okajima<\/strong>a, \u201cObservation of the Three-Dimensional Structure of Actin Bundles formed with Polycations\u201d, Biomacromolecules, 9, 537-542 (2008).<\/li>\n<li><strong>Y. Tanaka*, Y. Kawauchi, T. Kurokawa, H. Furukawa, T. Okajima, and J. P. Gong<\/strong>, \u201cLocalized Yielding around Crack Tips of Double-network Gels\u201d, Macromol. Rapid Commun., 29, 1514-1520 (2008).<\/li>\n<li><strong>H. Yamamura, K. Kimura, T. Okajima, H. Tokumoto, Y. Watamabe*<\/strong>, \u201cAffinity of Functional Groups for Membrane Surfaces: Implications for Physically Irreversible Fouling\u201d, Environ. Sci. Technol. 42(2008) 5310-5315.<\/li>\n<li><strong>Y. Mizutani, M. Tsuchiya, S. Hiratsuka, K. Kawahara, H. Tokumoto and T. Okajima*<\/strong>, \u201cElasticity of Living Cells on a Microarray during the Early Stages of Adhesion Measured by Atomic Force Microscopy\u201d, Jpn. J. Appl. Phys. 47(2008)6177-6180.<\/li>\n<li><strong>T. Okajima*, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura and H. Tokumoto<\/strong>, \u201d Stress Relaxation Measurement of Fibroblast Cells with Atomic Force Microscope \u201c, Jpn. J. Appl. Phys. (2007) 5552-5555<\/li>\n<li><strong>T. Okajima*, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura and H. Tokumoto<\/strong>, \u201cStress relaxation of HepG2 cells measured by atomic force microscopy\u201d, Nanotechnology 18 (2007) 084010<\/li>\n<li><strong>T. Okajima*, X.M. Tao, H. Azehara, H. Tokumoto<\/strong>, \u201cForce Spectroscopy on Single Polymer Incorporated into Polymer Gels\u201d, J. Nanosci. Nanotech. 7, 790?795 (2007).<\/li>\n<li><strong>H.-J. Kwon, A. Kakugo, T. Ura, T. Okajima, Y. Tanaka, H. Furukawa, Y. Osada and J.-P. Gong*<\/strong>, \u201cActin network formation by uni-directional polycation diffusion\u201d, Langmuir 23(2007)6257-6262<\/li>\n<li><strong>K. Hiroaki, T. Takagi, T. Okajima, M. Kinjo*<\/strong>, \u201cDNA microstructure based on self-assembly of 4-Sticky-End Holiday Junctions in Aqueous Solution \u201c, J. Nanosci. Nanotech. 7(2007)726-729.<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\uff1a\u591a\u7d30\u80de\u7cfb\u306e\u529b\u5b66\u7269\u6027\u8a08\u6e2c\u306e\u73fe\u72b6\u3001\u751f\u7269\u7269\u7406\uff08\u89e3\u8aac\uff09 62\u3001159-164(2022).<a class=\"blank\" href=\"https:\/\/www.jstage.jst.go.jp\/article\/biophys\/62\/3\/62_159\/_html\/-char\/ja\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b\u767a\u751f\u80da\u76ae\u8cea\u9818\u57df\u306e\u529b\u5b66\u6e2c\u5b9a\u3001\u819c\u300147\u3001269-272(2022).<\/li>\n<li><strong>\u85e4\u4e95\u88d5\u7d00\u3001\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u6cd5\uff1a\u7d30\u80de\u8868\u9762\u8fd1\u508d\u306e\u30ca\u30ce\u30e1\u30ab\u30cb\u30af\u30b9\u3001\u8868\u9762\u3068\u771f\u7a7a\u300163\u3001437-440 (2020).<a class=\"blank\" href=\"https:\/\/www.jstage.jst.go.jp\/article\/vss\/63\/8\/63_20180590\/_article\/-char\/ja\/\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u91cd\u5ddd\u79c0\u5b9f\u3001\u5409\u6751\u96c5\u6e80\u3001\u76ee\u826f\u88d5\u3001\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u30ca\u30ce\u8a08\u6e2c\u30fc\u96fb\u5b50\u7dda\u30fb\u5149\u30fb\u30d7\u30ed\u30fc\u30d6\u3092\u7528\u3044\u305f\u30ca\u30ce\u30fb\u30d0\u30a4\u30aa\u6750\u6599\u306e\u63a2\u7d22\u3068\u8a55\u4fa1 (\u30ca\u30ce\u5b66\u4f1a\u7de8\u3001\u8fd1\u4ee3\u79d1\u5b66\u793e\u30012020).<a class=\"blank\" href=\"https:\/\/www.kindaikagaku.co.jp\/science\/kd5029.htm\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u85e4\u4e95\u88d5\u7d00\u3001\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001AFM\u3092\u7528\u3044\u305f1\u7d30\u80de\u30fb\u7d30\u80de\u96c6\u56e3\u306e\u529b\u5b66\u7269\u6027\u8a08\u6e2c\u3001\u751f\u4f53\u306e\u79d1\u5b66\uff08\u7279\u96c6\u3000\u30e1\u30ab\u30ce\u30d0\u30a4\u30aa\u30ed\u30b8\u30fc\uff09\u300170\u3001273-278 (2019).<a class=\"blank\" href=\"http:\/\/www.igaku-shoin.co.jp\/journalDetail.do?journal=38439\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u85e4\u4e95\u88d5\u7d00\u3001\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001AFM\u306b\u3088\u308b\u591a\u7d30\u80de\u7cfb\u306e\u529b\u5b66\u6e2c\u5b9a\u3001\u9ad8\u5206\u5b50\u300168\u3001656-657 (2019).<a class=\"blank\" href=\"http:\/\/main.spsj.or.jp\/c5\/kobunshi\/kobu2019\/kobu1912.html\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u6dfa\u5ddd\u96c5\u3001\u5ca1\u5d8b\u5b5d\u6cbb\u3001\u5927\u897f\u6d0b<\/strong>\u3001\u8d70\u67fb\u578b\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\uff08\u65e5\u672c\u5206\u6790\u5316\u5b66\u4f1a\u7de8\u3001\u5206\u6790\u5316\u5b66\u5b9f\u6280\u30b7\u30ea\u30fc\u30ba\u6a5f\u5668\u5206\u6790\u7de815\uff09(2017).<a class=\"blank\" href=\"http:\/\/www.kyoritsu-pub.co.jp\/bookdetail\/9784320044548\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b1\u7d30\u80de\u30ec\u30aa\u30ed\u30b8\u30fc\u306e\u5b9a\u91cf\u8a08\u6e2c\u2500\u7d30\u80de\u306e\u500b\u6027\u3068\u30a8\u30eb\u30b4\u30fc\u30c9\u6027\u3001\u5fdc\u7528\u7269\u7406\u5b66\u4f1a\u8a8c\u300186\u30011052-1056 (2017).<a class=\"blank\" href=\"https:\/\/www.jsap.or.jp\/ap\/2017\/12\/ob861052.html\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u7d30\u80de\u30ca\u30ce\u30ec\u30aa\u30ed\u30b8\u30fc\uff1a\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u6cd5\u3001\u6708\u520a\u30bd\u30d5\u30c8\u30de\u30bf\u30fc\u3001 9\u6708\u53f7 (2018).<a class=\"blank\" href=\"https:\/\/www.fujisan.co.jp\/product\/1281701442\/new\/\" target=\"_blank\" rel=\"noopener noreferrer\">[book]<\/a><\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb\u3001\u9ad8\u6a4b\u4eae\u8f14<\/strong>\uff0c\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u3092\u7528\u3044\u305f\u7d30\u80de\u306e\u529b\u5b66\u7279\u6027\u8a08\u6e2c\uff08\u7b2c1\u7ae0\u30fb\u7b2c3\u7bc0\uff09\u3001\u7d30\u80de\u306e\u7279\u6027\u8a08\u6e2c\u30fb\u64cd\u4f5c\u3068\u5fdc\u7528\uff08\uff08\u7d44\u7e54\u5de5\u5b66\u30e9\u30a4\u30d6\u30e9\u30ea\uff0d\u30de\u30a4\u30af\u30ed\u30ed\u30dc\u30c6\u30a3\u30af\u30b9\u3068\u30d0\u30a4\u30aa\u306e\u878d\u5408\uff0d 1\uff09\uff08\u30b3\u30ed\u30ca\u793e\uff09 (2016)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\uff0c\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u3092\u7528\u3044\u305f\u7d30\u80de\u30ec\u30aa\u30ed\u30b8\u30fc\u7279\u6027\u306e\u8a08\u6e2c\uff08\u7b2c1\u7ae0\u30fb\u7b2c3\u7bc0\uff09\u3001\u4e09\u6b21\u5143\u30c6\u30a3\u30c3\u30b7\u30e5\u30a8\u30f3\u30b8\u30cb\u30a2\u30ea\u30f3\u30b0\uff5e\u7d30\u80de\u306e\u57f9\u990a\u30fb\u64cd\u4f5c\u30fb\u7d44\u7e54\u5316\u304b\u3089\u54c1\u8cea\u7ba1\u7406\u3001\u8131\u7d30\u80de\u5316\u307e\u3067\uff5e\uff08\u682a\u5f0f\u4f1a\u793eNTS\uff09 (2015)<\/li>\n<li><strong>\u6c34\u8c37\u7950\u8f14\uff0c\u7530\u4e2d\u826f\u660c\uff0c\u7530\u4e2d\u3042\u3084\uff0c\u4f4f\u53cb\u5f18\u4e8c\uff0c\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\uff0c\u30a4\u30aa\u30f3\u30b3\u30f3\u30c0\u30af\u30bf\u30f3\u30b9\u9855\u5fae\u93e1\uff1a\u7d30\u80de\u819c\u8868\u9762\u306e\u63fa\u3089\u304e\u3092\u8a08\u6e2c\u3059\u308b\u3001\u5149\u5b66-\u7d30\u80de\u6a5f\u80fd\u306b\u8feb\u308b\u975e\u67d3\u8272\u975e\u7834\u58ca\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u6280\u8853\u300144, (6\u6708\u53f7\uff09(2015)<\/li>\n<li><strong>\u9ad8\u6a4b\u4eae\u8f14\u3001\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b\u8d85\u9ad8\u901f\u7d30\u80de\u30e1\u30ab\u30cb\u30af\u30b9\u8a08\u6e2c\u6280\u8853\u3001\u30b1\u30df\u30ab\u30eb\u30a8\u30f3\u30b8\u30cb\u30e4\u30ea\u30f3\u30b0\uff08\u5148\u7aef\u8a08\u6e2c\u6280\u8853\u958b\u767a\u306e\u5c55\u671b:9\u6708\u53f7\uff09(2015)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\uff0c\u7d30\u80de\u306e\u7269\u7406\u5b66\uff1a\uff33\uff30\uff2d\u306b\u3088\u308b\u5b9a\u91cf\u8a08\u6e2c\u3001\u8868\u9762\u79d1\u5b66 35, 544-544(2014)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\uff0c\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b\u7d30\u80de\u529b\u5b66\u306e\u5b9a\u91cf\u8a08\u6e2c\uff08\u89e3\u8aac\uff09\u3001\u691c\u67fb\u6280\u8853 4,2-6(2014)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\uff0c\u8d70\u67fb\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u306b\u3088\u308b\u7d30\u80de\u7269\u6027\u6e2c\u5b9a\uff1a\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u3068\u30a4\u30aa\u30f3\u30b3\u30f3\u30c0\u30af\u30bf\u30f3\u30b9\u9855\u5fae\u93e1\uff08\u7dcf\u8aac\uff09\u3001\u5316\u5b66\u5de5\u696d 64(8), 612-617(2013)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb\u3001\u6c34\u8c37\u7950\u8f14<\/strong>\u3001\uff11\u7d30\u80de\u30ec\u30aa\u30ed\u30b8\u30fc\u6e2c\u5b9a\uff1a\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b\u7d30\u80de\u30ec\u30aa\u30ed\u30b8\u30fc\u8a08\u6e2c\u306e\u65b0\u624b\u6cd5\uff08\u7dcf\u8aac\uff09\u3001\u65e5\u672c\u751f\u7269\u7269\u7406\u5b66\u4f1a\u8a8c\u300c\u751f\u7269\u7269\u7406\u300d52, 230-233 (2012)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb\u3001\u6c34\u8c37\u7950\u8f14<\/strong>\u3001\u7d30\u80de\u529b\u5b66\u8a08\u6e2c\u306e\u305f\u3081\u306e\u30de\u30a4\u30af\u30ed\u52a0\u5de5\u57fa\u677f\u3092\u7528\u3044\u305f\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u6cd5\uff08\u7814\u7a76\u7d39\u4ecb\uff09\u3001\u65e5\u672c\u8868\u9762\u79d1\u5b66\u4f1a\u8a8c\u300c\u8868\u9762\u79d1\u5b66\u300d33, 461-466 (2012)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b\u7d30\u80de\u30ec\u30aa\u30ed\u30b8\u30fc\u6e2c\u5b9a\uff08\u7dcf\u8aac\uff09\u3001\u65e5\u672c\u819c\u5b66\u4f1a\u300c\u819c\u300d38, 76-81 (2013)<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb<\/strong>\u3001\u5b9f\u8df5\u7de8\u3000\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u306e\u4f7f\u3044\u65b9\u3000\u7b2c2\u7ae0\u3000\u8a66\u6599\u306e\u4f5c\u308a\u65b9\u30002.5\u3000\u30d0\u30a4\u30aa\u8a66\u6599\u306e\u6271\u3044, \u8d70\u67fb\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1-\u6b63\u3057\u3044\u5b9f\u9a13\u3068\u30c7\u30fc\u30bf\u89e3\u6790\u306e\u305f\u3081\u306b\u5fc5\u8981\u306a\u3053\u3068-\uff08\u5b9f\u9a13\u7269\u7406\u79d1\u5b66\u30b7\u30ea\u30fc\u30ba\u30006\uff09\uff082009.03\uff09<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb\u3001\u5fb3\u672c\u6d0b\u5fd7<\/strong>\u3001\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b\u751f\u7d30\u80de\u30ca\u30ce\u30ec\u30aa\u30ed\u30b8\u30fc\u8a08\u6e2c\u3001\u65e5\u672c\u30ec\u30aa\u30ed\u30b8\u30fc\u5b66\u4f1a\u8a8c36(2008)81-86<\/li>\n<li><strong>\u5ca1\u5d8b\u5b5d\u6cbb\u3001\u5fb3\u672c\u6d0b\u5fd7<\/strong>\u3001\u201d\u7b2c\uff11\uff11\u7ae0\uff1a\u56fa\u6db2\u754c\u9762\u30ca\u30ce\u9818\u57df\u306e\u529b\u5b66\u201d\u3001\u30ca\u30ce\u30c6\u30af\u306e\u305f\u3081\u306e\u7269\u7406\u5165\u9580\uff08\u5171\u7acb\u51fa\u7248\uff09\u65e5\u672c\u8868\u9762\u79d1\u5b66\u4f1a\u7de8\u96c6,162-177(2007)<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Takahiro Kotani, Tomohiro Matsuo, Megumi Yokobori, Yosuke Tsuboyama, Yuki Miyata, Yuki Fujii, Kaori Kuribayash [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"page-tpl-engcontents.php","meta":{"footnotes":""},"class_list":["post-107","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages\/107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/comments?post=107"}],"version-history":[{"count":16,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages\/107\/revisions"}],"predecessor-version":[{"id":2946,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages\/107\/revisions\/2946"}],"wp:attachment":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/media?parent=107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}