{"id":5,"date":"2014-02-24T03:25:25","date_gmt":"2014-02-24T03:25:25","guid":{"rendered":"http:\/\/lab-cte.dmz.co.jp\/?page_id=2"},"modified":"2024-03-10T15:38:27","modified_gmt":"2024-03-10T06:38:27","slug":"researchj-html","status":"publish","type":"page","link":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/researchj-html\/","title":{"rendered":"\u7814\u7a76\u5185\u5bb9"},"content":{"rendered":"<p class=\"mt20\">\u300c\u751f\u547d\u306e\u6700\u5c0f\u5358\u4f4d\u3067\u3042\u308b\u7d30\u80de\u3092\u7269\u7406\u5b66\u30fb\u60c5\u5831\u5de5\u5b66\u306e\u7acb\u5834\u3067\u7406\u89e3\u3057\u3001\u305d\u306e\u5de5\u5b66\u30fb\u533b\u5b66\u3078\u306e\u5fdc\u7528\u300d\u3092\u76ee\u6307\u3057\u3066\u7814\u7a76\u3057\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u5185\u5bb9\u306f\u3001\u7d30\u80de\u306e\u786c\u3055\u304b\u3089\u6b63\u5e38\u7d30\u80de\u3068\u7570\u5e38\u7d30\u80de\u3092\u898b\u5206\u3051\u308b\u6280\u8853\u306e\u958b\u767a\u3001\u7d30\u80de\u30b7\u30fc\u30c8\u30fb\u30de\u30a4\u30af\u30ed\u30d1\u30bf\u30fc\u30f3\u7d30\u80de\u3092\u7528\u3044\u305f\u7d30\u80de\u6a5f\u80fd\u30fb\u7d30\u80de\u60c5\u5831\u4f1d\u9054\u95a2\u6570\u306e\u7814\u7a76\u3001\u7d30\u80de\u30ca\u30ce\u8a08\u6e2c\u6cd5\u306e\u958b\u767a\u3001\u7b49\u3005\u3067\u3059\u3002\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u3001\u5149\u8a08\u6e2c\u6280\u8853\u3001\u5fae\u7d30\u52a0\u5de5\u6280\u8853\u306e\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u3092\u99c6\u4f7f\u3057\u3066\u3001\u5358\u4e00\u7d30\u80de\u304b\u3089\u7d30\u80de\u96c6\u56e3\u307e\u3067\u3001\u7d30\u80de\u3092\u64cd\u3063\u3066\u5b9f\u9a13\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u7d30\u80de\u751f\u7269\u5b66\u3068\u60c5\u5831\u5de5\u5b66\u306e\u5883\u754c\u9818\u57df\u306e\u65b0\u3057\u3044\u5206\u91ce\u306a\u306e\u3067\u3001\u7686\u3055\u3093\u306e\u67d4\u8edf\u306a\u767a\u60f3\u3067\u7814\u7a76\u304c\u3067\u304d\u307e\u3059\u3002\u751f\u7269\u3092\u7269\u7406\u30fb\u5de5\u5b66\u7684\u306b\u89e3\u660e\u3057\u305f\u3044\u65b9\u3001\u7d30\u80de\u306e\u5de5\u5b66\u7684\u306a\u5fdc\u7528\u306b\u8208\u5473\u306e\u3042\u308b\u65b9\u3001\u4e00\u7dd2\u306b\u7814\u7a76\u3057\u307e\u305b\u3093\u304b\u3002<a href=\"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-content\/uploads\/2024\/03\/98fdd4ffb70435433a49aa5037059f81.pdf\">\u7814\u7a76\u5ba4\u7d39\u4ecb\uff08web\u63b2\u8f09\uff092023\u5e74\u5ea6<\/a><\/p>\n<p class=\"noindent mt10\"><a class=\"blank\" href=\"http:\/\/www.ist.hokudai.ac.jp\/netjournal\/net_25_1.html\" target=\"_blank\" rel=\"noopener noreferrer\">\u7d30\u80de\u306e\u300c\u529b\u300d\u3092\u7cbe\u5bc6\u306b\u8a08\u6e2c\u3059\u308b\u624b\u6cd5\u3092\u958b\u767a\uff1a\u5de5\u5b66\u7684\u306a\u8996\u70b9\u304b\u3089\u751f\u547d\u306e\u8b0e\u306b\u8feb\u308b<\/a><\/p>\n<h2 id=\"r4\">\u751f\u4f53\u7d44\u7e54\u306e\u786c\u3055\u3092\u5b9a\u91cf\u5316\u3059\u308b\uff08\u7d44\u7e54\u30ca\u30ce\u529b\u5b66\u8a08\u6e2c\uff09<\/h2>\n<p>\u751f\u4f53\u7d44\u7e54\u306f\u3001um\u30aa\u30fc\u30c0\u30fc\u304b\u3089mm\u30aa\u30fc\u30c0\u30fc\u3067\u5287\u7684\u306a\u5f62\u614b\u5909\u5316\u3092\u793a\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u30c0\u30a4\u30ca\u30df\u30c3\u30af\u306a\u751f\u4f53\u7d44\u7e54\u306e\u786c\u3055\u3092\u30ca\u30ce\u30b9\u30b1\u30fc\u30eb\u3067\u8a08\u6e2c\u3059\u308b\u624b\u6cd5\u3068\u3057\u3066\u3001AFM\u304c\u3042\u308b\u304c\u3001AFM\u30c7\u30fc\u30bf\u89e3\u6790\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u5f62\u614b\u306e\u5f71\u97ff\u306f\u9577\u3089\u304f\u7121\u8996\u3055\u308c\u3066\u304d\u305f\u3002\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u751f\u4f53\u7d44\u7e54\u8868\u9762\u306e\u50be\u659c\u3092\u8003\u616e\u3057\u3066\u3001\u771f\u306e\u751f\u4f53\u7d44\u7e54\u306e\u786c\u3055\u3092\u5b9a\u91cf\u5316\u3067\u304d\u308bAFM\u89e3\u6790\u30e2\u30c7\u30eb\u3092\u63d0\u6848\u3057\u3001\u751f\u4f53\u7d44\u7e54\u306e\u5f3e\u6027\u7387\u306e\u5b9a\u91cf\u8a08\u6e2c\u6cd5\u3092\u78ba\u7acb\u3057\u305f\uff08Fujii et al. AIP Adv., 2019\uff09\u3002<\/p>\n<p><a href=\"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-content\/uploads\/2020\/03\/167e7baf0956a5289e42003fbf5faf44.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1731 size-full\" src=\"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-content\/uploads\/2020\/03\/167e7baf0956a5289e42003fbf5faf44-e1585131453883.png\" alt=\"\" width=\"600\" height=\"202\" \/><\/a><\/p>\n<h2 id=\"r4\">\u751f\u4f53\u7d44\u7e54\u306f\u7d30\u80de\u9593\u306e\u786c\u3055\u3092\u8a8d\u8b58\u3057\u3066\u3044\u308b\uff01 \uff08\u7d44\u7e54\u7269\u7406\u5b66\uff09<\/h2>\n<p>1\u7d30\u80de\u7cfb\u306b\u304a\u3044\u3066\u3001\u7d30\u80de\u306e\uff62\u727d\u5f15\u529b\uff08\u5f35\u529b\uff09\uff63\u3068\uff62\u786c\u3055\uff63\u306e\u8a08\u6e2c\u306f\u3001\u7d30\u80de\u751f\u7269\u5b66\u6a5f\u80fd\u306e\u7406\u89e3\u306b\u91cd\u8981\u3067\u3042\u308b\uff08Roca-Cusachs et al. Nat. Cell Biol. 2017\uff09\u3002\u8fd1\u5e74\u3001\u591a\u7d30\u80de\u7cfb\u306b\u304a\u3044\u3066\u3082\u3001\u7d30\u80de\u9593\u306e\u5f35\u529b\u5206\u5e03\u304c\u89e3\u304d\u660e\u304b\u3055\u308c\u3066\u304d\u305f\u304c\u3001\u7d30\u80de\u9593\u306e\u786c\u3055\u5206\u5e03\u306e\u8a73\u7d30\u306f\u4e0d\u660e\u3067\u3042\u3063\u305f\u3002\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u7d44\u7e54\u30e1\u30ab\u30cb\u30af\u30b9\u306e\u305f\u3081\u306e\u5e83\u7bc4\u56f2\u8a08\u6e2c\u304c\u53ef\u80fd\u306a\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\uff08AFM\uff09\u3092\u69cb\u7bc9\u3057\u3001\u4e0a\u76ae\u7d30\u80de\u30b7\u30fc\u30c8\uff08\u5358\u5c64\u7d30\u80de\uff09\u306e\u5f3e\u6027\u7387\u30de\u30c3\u30d4\u30f3\u30b0\u6e2c\u5b9a\u306b\u6210\u529f\u3057\u3001\u7d30\u80de\u9593\u306e\u786c\u3055\u306e\u7a7a\u9593\u76f8\u95a2\u306e\u5b58\u5728\u3092\u898b\u3044\u3060\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u304b\u3089\u3001\u7d30\u80de\u9593\u3067\u306f\u7d30\u80de\u306e\u786c\u3055\u306e\u60c5\u5831\u4f1d\u9054\u3092\u884c\u3044\u306a\u304c\u3089\u3001\u5404\u3005\u306e\u7d30\u80de\u306e\u786c\u3055\u304c\u8abf\u7bc0\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\uff08Fujii et al. Biophys. J., 2019\uff09\u3002<br \/>\n<a href=\"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-content\/uploads\/2020\/03\/7859b3b863e65bd21e1c9532cae830af-e1585131489897.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1732\" src=\"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-content\/uploads\/2020\/03\/7859b3b863e65bd21e1c9532cae830af-e1585131489897.png\" alt=\"\" width=\"600\" height=\"204\" \/><\/a><\/p>\n<h2 id=\"r4\">\u591a\u91cd\u5468\u6ce2\u6570\u30d5\u30a9\u30fc\u30b9\u30e2\u30b8\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3AFM\u6cd5\uff1a\u7d30\u80de\u30ec\u30aa\u30ed\u30b8\u30fc\u306e\u9ad8\u901f\u30de\u30c3\u30d4\u30f3\u30b0(\u7d30\u80de\u8a08\u6e2c\u5b66)<\/h2>\n<p>AFM\u3092\u7528\u3044\u305f\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u3084\u30de\u30c3\u30d4\u30f3\u30b0\u306b\u3088\u3063\u3066\uff0c\u7d30\u80de\u5185\u90e8\u306e\u5f3e\u6027\u7387\u306e\u4e0d\u5747\u4e00\u6027\u3092\u89b3\u5bdf\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\uff0e\u4e00\u65b9\u3067\uff0c\u7d30\u80de\u306e\u5f3e\u6027\u7387\u306f\u4f4e\u5468\u6ce2\u6570\u9818\u57df\uff08&lt;1kHz\uff09\u306b\u304a\u3044\u3066\u7d30\u80de\u56fa\u6709\u306e\u5468\u6ce2\u6570\u7279\u6027\u3092\u793a\u3059\u305f\u3081(Fabry et al. Phys. Rev. Lett., 2001) \u3001\u5f3e\u6027\u7387\u306e\u5468\u6ce2\u6570\u7279\u6027\u306e\u8a08\u6e2c\u306f\u91cd\u8981\u3067\u3042\u308b\uff0e\u3053\u308c\u307e\u3067\u3001\u30d5\u30a9\u30fc\u30b9\u30e2\u30b8\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3AFM\u6cd5\uff08Radmacher et al. Science 1992\uff09\u3092\u7528\u3044\u3066\u3001\uff11\u3064\u306e\u5468\u6ce2\u6570\u306b\u304a\u3051\u308b\u7d30\u80de\u306e\u5f3e\u6027\u7387\u306e\u30de\u30c3\u30d4\u30f3\u30b0\u304c\u53ef\u80fd\u3067\u3042\u3063\u305f\u304c\uff0c\u7d30\u80de\u5f3e\u6027\u7387\u306e\u5468\u6ce2\u6570\u7279\u6027\u306e\u30de\u30c3\u30d4\u30f3\u30b0\u306f\u56f0\u96e3\u3067\u3042\u3063\u305f\uff0e\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u591a\u91cd\u5468\u6ce2\u6570\u30d5\u30a9\u30fc\u30b9\u30e2\u30b8\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u6cd5\u3092\u958b\u767a\u3057\uff0c\u7d30\u80de\u5f3e\u6027\u7387\u306e\u5468\u6ce2\u6570\u7279\u6027\u306e\u30de\u30c3\u30d4\u30f3\u30b0\u306b\u6210\u529f\u3057\uff0c\u5358\u4e00\u7d30\u80de\u5185\u306e\u529b\u5b66\u7279\u6027\u306e\u7a7a\u9593\u5206\u5e03\u3092\u660e\u3089\u304b\u306b\u3057\u305f\uff0e\u672c\u6280\u8853\u306f\u7d30\u80de\u5185\u90e8\u69cb\u9020\u306e\u529b\u5b66\u7684\u53ef\u8996\u5316\u3084\u304c\u3093\u7d30\u80de\u306e\u529b\u5b66\u7684\u9ad8\u901f\u8a3a\u65ad\u6280\u8853\u3078\u306e\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u308b(Takahashi and Okajima. Appl. Phys. Lett., 2015)\uff0e<\/p>\n<figure class=\"center\"><img decoding=\"async\" src=\"\/labo\/cell\/wp-content\/themes\/lab-cte\/images\/fig04.jpg\" alt=\"\" width=\"600\" height=\"280&quot;\" \/><\/figure>\n<h2 id=\"r1\">\u5358\u4e00\u7d30\u80de\u8a3a\u65ad\uff1a\u500b\u3005\u306e\u7d30\u80de\u306e\u500b\u6027\u306f\uff1f \uff08\u7d30\u80de\u533b\u5de5\u5b66\uff09<\/h2>\n<p>\u7d30\u80de\u75c5\u7406\u691c\u67fb\u306f\uff0c\u304c\u3093\u7d30\u80de\u306e\u65e9\u671f\u767a\u898b\u3084\u816b\u760d\u7d30\u80de\u306e\u5224\u5b9a\u306e\u91cd\u8981\u306a\u533b\u7642\u691c\u67fb\u6280\u8853\u3067\u3042\u308b\uff0e\u4e00\u822c\u306b\uff0c\u7d30\u80de\u75c5\u7406\u691c\u67fb\u306b\u304a\u3044\u3066\uff0c\u514d\u75ab\u67d3\u8272\u3057\u305f\u7d30\u80de\u3092\u5149\u5b66\u9855\u5fae\u93e1\u3067\u89b3\u5bdf\u3057\uff0c\u7d30\u80de\u5f62\u614b\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u767a\u73fe\u91cf\u7b49\u304b\u3089\u7d30\u80de\u306e\u75c5\u614b\u3092\u8a3a\u65ad\u3059\u308b\uff0e\u4e00\u65b9\u3067\uff0c\u8fd1\u5e74\uff0c\u7d30\u80de\u306e\u5f3e\u6027\u7387\u306e\u9055\u3044\u304b\u3089\uff0c\u304c\u3093\u7d30\u80de\u3068\u6b63\u5e38\u7d30\u80de\u3068\u3092\u8a3a\u65ad\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u304d\u305f\uff08Cross et al. Nat. Nanotech., 2007\uff09\uff0e\u304c\u3093\u7d30\u80de\u306f\u6b63\u5e38\u7d30\u80de\u3088\u308a\u6709\u610f\u306b\u67d4\u3089\u304b\u304f\uff0c\u7d30\u80de\u306e\u5f3e\u6027\u7387\u304c\uff0c\u304c\u3093\u7d30\u80de\u691c\u67fb\u306e\u6307\u6a19\u3068\u3057\u3066\u5229\u7528\u3067\u304d\uff0c\u304c\u3093\u7d30\u80de\u691c\u67fb\u306e\u5b9a\u91cf\u5316\u304c\u671f\u5f85\u3055\u308c\u308b\uff0e\u3053\u308c\u3092\u5b9f\u73fe\u3059\u308b\u305f\u3081\u306b\u306f\uff0c\u518d\u73fe\u6027\u306e\u3042\u308b\u7d30\u80de\u529b\u5b66\u7269\u6027\u3092\u5982\u4f55\u306b\u8a08\u6e2c\u3059\u308b\u304b\uff0c\u305d\u306e\u624b\u6cd5\u306e\u78ba\u7acb\u304c\u6025\u52d9\u3067\u3042\u308b\uff0e\u5f53\u7814\u7a76\u5ba4\u3067\u306f\uff0c\u7d30\u80de\u306e\u529b\u5b66\u7279\u6027\u3092\u6700\u3082\u9ad8\u7cbe\u5ea6\u306b\u8a08\u6e2c\u3067\u304d\u308b\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\uff08Atomic Force Microscopy: AFM\uff09\u3092\u7528\u3044\u3066\uff0c\u591a\u6570\u7d30\u80de\u306e\u529b\u5b66\u8a08\u6e2c\u6280\u8853\u3092\u958b\u767a\u3057\u305f\uff0e\u305d\u3057\u3066\uff0c\u7d30\u80de\u529b\u5b66\u7279\u6027\u30c7\u30fc\u30bf\u304b\u3089\uff0c\u7d30\u80de\u56fa\u6709\u529b\u5b66\u91cf\u3092\u62bd\u51fa\u3057\uff0c\u7d30\u80de\u529b\u5b66\u7279\u6027\u306e\u500b\u6027\u306e\u5b9a\u91cf\u5316\u306b\u6210\u529f\u3057\u305f (Cai et al. Biophys. J, 2013)\uff0e<\/p>\n<figure class=\"center\"><img loading=\"lazy\" decoding=\"async\" src=\"\/labo\/cell\/wp-content\/themes\/lab-cte\/images\/fig01.jpg\" alt=\"\" width=\"600\" height=\"280\" \/><\/figure>\n<h2 id=\"r2\">\u7d30\u80de\u819c\u306f\u63fa\u3089\u3044\u3067\u3044\u308b\uff01\uff1a\u30a4\u30aa\u30f3\u30b3\u30f3\u30c0\u30af\u30bf\u30f3\u30b9\u9855\u5fae\u93e1\uff08\u7d30\u80de\u7269\u7406\u5b66\uff09<\/h2>\n<p>\u30a4\u30aa\u30f3\u30b3\u30f3\u30c0\u30af\u30bf\u30f3\u30b9\u9855\u5fae\u93e1\uff08SICM\uff09\u306f\uff0c\u67d4\u3089\u304b\u3044\u751f\u7d30\u80de\u8868\u9762\u819c\u306e\u5f62\u72b6\u3092\u6975\u3081\u3066\u9ad8\u3044\u5206\u89e3\u80fd\u3067\u8a08\u6e2c\u3067\u304d\u308b\u8d70\u67fb\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u3067\u3042\u308b\uff0eSICM\u306f\uff0c\u96fb\u89e3\u8cea\u6eb6\u6db2\u304c\u6e80\u305f\u3055\u308c\u305f\uff0c\u5148\u7aef\u5f84100nm\u7a0b\u306e\u5fae\u5c0f\u5b54\u3092\u3082\u3064\u30ac\u30e9\u30b9\u30ca\u30ce\u30d4\u30da\u30c3\u30c8\u3092\u30d7\u30ed\u30fc\u30d6\u3068\u3057\u3066\u7528\u3044\u308b\uff0e\u305d\u3057\u3066\uff0c\u5fae\u5c0f\u5b54\u3092\u6d41\u308c\u308b\u30a4\u30aa\u30f3\u96fb\u6d41\u3092\u6e2c\u5b9a\u3059\u308b\uff0e\u30d4\u30da\u30c3\u30c8\u63a2\u91dd\u304c\u7d30\u80de\u8868\u9762\u306b\u8fd1\u3065\u304f\u3068\uff0c\u7d30\u80de\u8868\u9762\u306e\u5b58\u5728\u306b\u3088\u308b\u201c\u62b5\u6297\u201d\u306b\u3088\u308a\uff0c\u5fae\u5c0f\u5b54\u3092\u6d41\u308c\u308b\u30a4\u30aa\u30f3\u96fb\u6d41\u91cf\u304c\u6e1b\u5c11\u3059\u308b\uff0e\u3053\u306e\u73fe\u8c61\u3092\u5229\u7528\u3057\u3066\uff0c\u975e\u63a5\u89e6\u3067\u8868\u9762\u4f4d\u7f6e\u3092\u30ca\u30ce\u30e1\u30fc\u30c8\u30eb\u306e\u7cbe\u5ea6\u3067\u691c\u77e5\u3067\u304d\u308b\uff0e\u6700\u8fd1\uff0c\u5f53\u7814\u7a76\u5ba4\u3067\u306f\uff0cSICM\u3092\u7528\u3044\u305f\u751f\u7d30\u80de\u8868\u9762\u306e\u63fa\u3089\u304e\u8a08\u6e2c\u6cd5\u3092\u958b\u767a\u3057\u305f\uff0e\u305d\u3057\u3066\uff0c\u4e0a\u76ae\u7d30\u80de\u30b7\u30fc\u30c8\u306e\u7d30\u80de\u8868\u9762\u306e\u7a7a\u9593\u63fa\u3089\u304e\u3092\u30ca\u30ce\u30b9\u30b1\u30fc\u30eb\u3067\u8a08\u6e2c\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u305f (Y. Mizutani et al. Appl. Phys. Lett., 2013)\uff0e<\/p>\n<figure class=\"center\"><img loading=\"lazy\" decoding=\"async\" src=\"\/labo\/cell\/wp-content\/themes\/lab-cte\/images\/fig02.jpg\" alt=\"\" width=\"600\" height=\"280\" \/><\/figure>\n<h2 id=\"r3\">\u7d30\u80de\u5185\u90e8\u3092\u529b\u304c\u4f1d\u64ad\u3059\u308b\uff01\uff1a\u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\uff08\u7d30\u80de\u60c5\u5831\u5de5\u5b66\uff09<\/h2>\n<p>\u7d30\u80de\u306f\uff0c\u63a5\u7740\u70b9\u3092\u4ecb\u3057\u3066\u5468\u56f2\u306e\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30af\u30b9\u3068\u63a5\u7740\u3059\u308b\uff0e\u7d30\u80de\u3068\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30af\u30b9\u3068\u306e\u9593\u306b\u50cd\u304f\u529b\u306f\uff0c\u7d30\u80de\u9aa8\u683c\u3092\u4ecb\u3057\u3066\u7d30\u80de\u5185\u90e8\u306e\u7d30\u80de\u6838\u3084\u305d\u306e\u4ed6\u306e\u7d30\u80de\u5185\u5c0f\u5668\u5b98\u306b\u9577\u8ddd\u96e2\u306b\u4f1d\u64ad\u3057\uff0c\u529b\u306b\u3088\u308b\u7d30\u80de\u5185\u69cb\u9020\u306e\u5909\u5316\u304c\uff0c\u907a\u4f1d\u5b50\u767a\u73fe\u7b49\u306e\u7d30\u80de\u6a5f\u80fd\u306e\u5236\u5fa1\u3068\u5bc6\u63a5\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b(Wang et al. Nat. Rev. Mol. Cell Biol., 2009)\uff0e\u3057\u304b\u3057\uff0c\u7d30\u80de\u9aa8\u683c\u3092\u4ecb\u3059\u308b\u529b\u4f1d\u64ad\u306e\u76f4\u63a5\u89b3\u5bdf\u6cd5\u306f\u306a\u304b\u3063\u305f\uff0e\u5f53\u7814\u7a76\u5ba4\u3067\u306f\uff0c\u96e2\u6563\u7684\u306a\u529b\u3092\u9ad8\u611f\u5ea6\u306b\u8a08\u6e2c\u3067\u304d\u308b\u30de\u30a4\u30af\u30ed\u30dd\u30b9\u30c8\u57fa\u677f\u3068\u7d30\u80de\u306eAFM\u6cd5\u3092\u4f75\u7528\u3057\u305f\u65b0\u624b\u6cd5\u3092\u7528\u3044\u3066\uff0c\u7279\u5b9a\u306e\u5468\u6ce2\u6570\uff08&lt;1Hz\uff09\u306b\u304a\u3044\u3066\uff0c\u7d30\u80de\u9aa8\u683c\u3092\u4ecb\u3059\u308b\u529b\u4f1d\u64ad\u3092\u76f4\u63a5\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u305f\uff0e\u672c\u8a08\u6e2c\u6280\u8853\u306f\uff0c\u7d30\u80de\u5185\u306e\u8907\u96d1\u306a\u9aa8\u683c\u69cb\u9020\u304c\u751f\u307f\u51fa\u3059\u529b\u4f1d\u64ad\u95a2\u6570\u3092\u8abf\u3079\u308b\u6709\u7528\u306a\u624b\u6cd5\u306b\u306a\u308b\u3068\u671f\u5f85\u3067\u304d\u308b\uff08Okada et al. Appl. Phys. Lett., 2011\uff09\uff0e<\/p>\n<figure class=\"center\"><img loading=\"lazy\" decoding=\"async\" src=\"\/labo\/cell\/wp-content\/themes\/lab-cte\/images\/fig03.jpg\" alt=\"\" width=\"600\" height=\"280\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>\u300c\u751f\u547d\u306e\u6700\u5c0f\u5358\u4f4d\u3067\u3042\u308b\u7d30\u80de\u3092\u7269\u7406\u5b66\u30fb\u60c5\u5831\u5de5\u5b66\u306e\u7acb\u5834\u3067\u7406\u89e3\u3057\u3001\u305d\u306e\u5de5\u5b66\u30fb\u533b\u5b66\u3078\u306e\u5fdc\u7528\u300d\u3092\u76ee\u6307\u3057\u3066\u7814\u7a76\u3057\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u5185\u5bb9\u306f\u3001\u7d30\u80de\u306e\u786c\u3055\u304b\u3089\u6b63\u5e38\u7d30\u80de\u3068\u7570\u5e38\u7d30\u80de\u3092\u898b\u5206\u3051\u308b\u6280\u8853\u306e\u958b\u767a\u3001\u7d30\u80de\u30b7\u30fc\u30c8\u30fb\u30de\u30a4\u30af\u30ed\u30d1\u30bf\u30fc\u30f3\u7d30\u80de\u3092\u7528\u3044\u305f\u7d30\u80de [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-5","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages\/5","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":37,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":2707,"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/pages\/5\/revisions\/2707"}],"wp:attachment":[{"href":"https:\/\/www.ist.hokudai.ac.jp\/labo\/cell\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}