Recent publications

2025

T. Oh, M. Kim, G.-S. Kang, S.-J. Ye, C. Choi, W. Park, M. Hay, H. Hirata, and G.-O. Ahn. Understanding Immune Cell Adaptation to Tumor Hypoxia for Maximized Therapeutic Efficacy of Immunotherapy: Biology and Non-Invasive Imaging Application. Cancer Research and Treatment, E-pub ahead (2025). https://doi.org/10.4143/crt.2025.200 (Open Access)

Y. Arai, M. Taguchi, O. Mitarai, I. Yamaguchi, H. Sato-Akaba, S. Matsumoto, M. Miyake, and H. Hirata. Three-dimensional electron paramagnetic resonance (EPR) imaging of an X-ray-irradiated bovine tooth: A feasibility study. Radiation Measurements, 181, 107381 (2025). https://doi.org/10.1016/j.radmeas.2025.107381

2024

J. Oh, C. U. Koo, J.-I. Park, K. Choi, J. Lee, H. Hirata, and S.-J. Ye. Accuracy enhancement of L-band EPR tooth dosimetry by implementing multiple harmonic detection. Radiation Measurements, 176, 107185 (2024). https://doi.org/10.1016/j.radmeas.2024.107185

K. Sawami, T. Naganuma, H. Yabe, T. Taki, N. J. Stewart, Y. Uchio, N. Takeda, N. Hatae, T. Hashimoto, H. Hirata, and S. Matsumoto. Parahydrogen-Induced 13C Hyperpolarizer Using a Flow Guide for Magnetic Field Cycling to Evoke 1H-13C Spin Order Transfer Toward Metabolic MRI. IEEE Transactions on Biomedical Engineering, 71, 2224-2231 (2024). https://doi.org/10.1109/tbme.2024.3365195

M. Oba, M. Taguchi, Y. Kudo, K. Yamashita, H. Yasui, S. Matsumoto, I. A. Kirilyuk, O. Inanami, and H. Hirata. Partial Acquisition of Spectral Projections Accelerates Four-dimensional Spectral-spatial EPR Imaging for Mouse Tumor Models: A Feasibility Study. Molecular Imaging and Biology, 26, 459-472 (2024). https://doi.org/10.1007/s11307-024-01924-y

H. Sato-Akaba, T. Sakai, and H. Hirata. Generation of transmission wave with low AM noise for sub-GHz CW-EPR spectrometer. Journal of Magnetic Resonance, 360, 107633 (2024). https://doi.org/10.1016/j.jmr.2024.107633

2023

C. U. Koo, J.-I. Park, J. Oh, K. Choi, J. Yoon, H. Hirata, and S.-J. Ye. Frequency-fixed Motion Compensation System for in-vivo Electron Paramagnetic Resonance Tooth Dosimetry. Journal of Magnetic Resonance, 353, 107520 (2023). https://doi.org/10.1016/j.jmr.2023.107520

R. Nakaoka, K. Kato, K. Yamamoto, H. Yasui, S. Matsumoto, I. A. Kirilyuk, V. V. Khramtsov, O. Inanami, and H. Hirata. Electron Paramagnetic Resonance Implemented with Multiple Harmonic Detections Successfully Maps Extracellular pH In Vivo. Analytical Chemistry, 95, 3940-3950 (2023). https://doi.org/10.1021/acs.analchem.2c03194 (Open Access)

R. Sato, A. Utagawa, K. Fushimi, F. Li, T. Isono, K. Tajima, T. Satoh, S. Sato, H. Hirata, Y. Kikkawa, and T. Yamamoto. Molecular Weight-Dependent Oxidation and Optoelectronic Properties of Defect-Free Macrocyclic Poly(3-hexylthiophene). Polymers, 15, 666 (2023). https://doi.org/10.3390/polym15030666 (Open Access)

2022

T. Kawai, M. Matsuo, Y. Takakusagi, K. Saito, F. Hyodo, N. Devasahayam, S. Matsumoto, S. Kishimoto, H. Yasui, K. Yamamoto, and M. C. Krishna. Continuous monitoring of post-irradiation reoxygenation and cycling hypoxia using electron paramagnetic resonance imaging. NMR in Biomedicine, 35, e4783 (2022). https://doi.org/10.1002/nbm.4783 (Open Access)

K. Choi, C. U. Koo, J. Oh, J.-I. Park, H. Hirata, and S.-J. Ye. Development of electron paramagnetic resonance magnet system for in vivo tooth dosimetry. Concepts in Magnetic Resonance Part B, Magnetic Resonance Engineering, 2022, 7332324 (2022). https://doi.org/10.1155/2022/7332324

H. Hirata and H. M. Swartz. RF/Microwave Resonators for Preclinical and Clinical EPR Applications: Current Status and Challenges. Applied Magnetic Resonance, 53, 167-191 (2022). https://doi.org/10.1007/s00723-021-01413-3

Y. Nakai, I. Yamaguchi, H. Hirata, H. M. Swartz, A. B. Flood, B. B. Williams, W. Schreiber, and M. Miyake. Effects of Ultraviolet Rays on L-Band In Vivo EPR Dosimetry Using Tooth Enamel. Applied Magnetic Resonance, 53, 305-318 (2022). https://doi.org/10.1007/s00723-021-01340-3

N. J. Stewart, T. Sato, N. Takeda, H. Hirata, and S. Matsumoto. Hyperpolarized 13C Magnetic Resonance Imaging as a Tool for Imaging Tissue Redox State, Oxidative Stress, Inflammation, and Cellular Metabolism. Antioxidants & Redox Signaling, 36, 81-94 (2022). https://doi.org/10.1089/ars.2021.0139 (Open Access)

K. Kimura, N. Iguchi, H. Nakano, H. Yasui, S. Matsumoto, O. Inanami, and H. Hirata. Redox-Sensitive Mapping of a Mouse Tumor Model Using Sparse Projection Sampling of Electron Paramagnetic Resonance. Antioxidants & Redox Signaling, 36, 57-69 (2022). https://doi.org/10.1089/ars.2021.0003 (Open Access)

2021

N. Miura, C. Mushti, D. Sail, J. E. AbuSalim, K. Yamamoto, J. R. Brender, T. Seki, D. I. AbuSalim, S. Matsumoto, K. A. Camphausen, M. C. Krishna, R. E. Swenson, and A. H. Kesarwala. Synthesis of [1-13C-5-12C]-alpha-ketoglutarate enables noninvasive detection of 2-hydroxyglutarate. NMR in Biomedicine, 34, e4588 (2021). https://doi.org/10.1002/nbm.4588

F. Cheng, T. Shibata, Y. Aoki, and H. Hirata. A 2.0-GHz compact ESR spectrometer for monitoring automobile lubrication oil degradation. Journal of Magnetic Resonance, 332, 107081 (2021). https://doi.org/10.1016/j.jmr.2021.107081

D. A. Komarov, A. Samouilov, H. Hirata, and J. L. Zweier. High fidelity triangular sweep of the magnetic field for millisecond scan EPR imaging. Journal of Magnetic Resonance, 329, 107024 (2021). https://doi.org/10.1016/j.jmr.2021.107024

N. J. Stewart and S. Matsumoto. Biomedical Applications of the Dynamic Nuclear Polarization and Parahydrogen Induced Polarization Techniques for Hyperpolarized 13C MR Imaging. Magnetic Resonance in Medical Sciences, 20, 1-17 (2021). https://doi.org/10.2463/mrms.rev.2019-0094

N. J. Stewart, H. Nakano, S. Sugai, M. Tomohiro, Y. Kase, Y. Uchio, T. Yamaguchi, Y. Matsuo, T. Naganuma, N. Takeda, I. Nishimura, H. Hirata, and S. Matsumoto. Hyperpolarized 13C MRI of Fumarate Metabolism by Parahydrogen‐induced Polarization: A Proof‐of‐Concept In Vivo Study. ChemPhysChem, 22, 915-923 (2021). https://doi.org/10.1002/cphc.202001038

J.-I. Park, K. Choi, C. U. Koo, J. Oh, H. Hirata, H. M. Swartz, and S.-J. Ye. Dependence of Radiation-induced Signals on Geometry of Tooth Enamel Using a 1.15 GHz Electron Paramagnetic Resonance Spectrometer. Health Physics, 120, 152-162 (2021). https://doi.org/10.1097/HP.0000000000001292