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Research projects
Ongoing Projects
Grant # LR002, H. Hirata (PI), 2/10/2011–3/31/2014, JPY 112,000,000 ($1,120,000)
Japan Society for the Promotion of Science (JSPS)
Funding Program of Next Generation World-Leading Researchers (NEXT Program)
Title: Imaging of chiral molecules based on
magnetic resonance
The Goal of this project is to develop a molecular imaging method to vosualize chiral molecules that are labeled with isotopic nitroxyl radicals.
Role: PI
Past Projects
Grant # 21360193, H. Hirata (PI), 4/1/2009–3/31/12, JPY 13,600,000 ($136,000)
Japan Society for the Promotion of Science (JSPS)
Title: Functional Electron Paramagnetic Resonance Imaging for Brain/Neuroscience Studies.
The major goal of this project is to develop advanced technologies of functional electron paramagnetic resonance imaging for small animals, especially for brain/neuroscience studies.
Role: PI
Note: This program was early ended due to the NEXT Program of JSPS.
H. Hirata (PI), 10/1/08–3/31/12, JPY 43,000,000 ($430,000)
Japan Science and Technology Agency (JST)
Title: Development of fast CW-EPR imaging.
The goal of this project is to develop a method of fast continuous-wave electron paramagnetic resonance imaging. The target data acquisition time of 3D EPR imaging is less than 5 s.
Role: PI
Note: This program was early ended due to the NEXT Program of JSPS.
![](img/TEMPOL-images.jpg)
Temporal changes of free radical distribution obtained at the inrerval of 5.8 s. Rev Sci Instrum 79, article no. 123701 (2008).
Grant # 20656065, H. Hirata (PI), 4/01/08–3/31/11, JPY 3,500,000 ($35,000)
Japan Society for the Promotion of Science (JSPS)
Title: Development of Superresolution Electron Paramagnetic Resonance Imaging.
The major goal of this project is to develop a method of superresolution processing in EPR imaging to enhance the spatial resolution.
Role: PI
![](img/Mouse-slice-image.jpg)
Resolution-recovery for CW-EPR imaging with a live mouse. Magn Reson Med (2009, in press)
Grant # 19390322, H. Fujii (PI), 4/01/07–3/31/10, JPY 14,400,000 ($144,000)
Japan Society for the Promotion of Science (JSPS)
Title: Functional Imaging with a Unified ESR/MRI Instrument.
The major goal of this project is to develop a new method for small animal imaging based on ESR and MRI modalities.
Role: Co-Investigator
![](img/EPR-NMR_coimaging.jpg)
Co-registration of NMR and EPR imaging. J Magn Reson 184, 29-38 (2007).
Contract # U19 AI067733-01, H. Hirata (Subcontract PI), 10/1/08–7/31/09 $24,840
NIH/NIAID (Subcontract between the University of Rochester and Hokkaido University)
This subcontract is intended to lead to the development of a 1.2-GHz microwave resonator for use in EPR dosimetry on human tooth in vivo. This is part of a research effort of the Center for Biophysical Assessment and Risk Management Following Radiation (Director P. Okunieff) at the University of Rochester Medical Center, supported by NIAID’s Biodefense Research Program.
Role: Subcontract-PI